C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2409154
The invention relates to compositions, kits and methods for identifying, detecting, and modulating the differentiation, growth, and/or maturation of Th1 or Th2 cells. The invention further relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating a Th1- or Th2- associated condition. A variety of markers are provided, wherein changes in the levels of expression of one or more of the markers is correlated with the presence of a Th1 or Th2 cell or Th1- or Th2-associated condition.
L'invention concerne des compositions, des trousses et des méthodes destinées à identifier, détecter et moduler la différentiation, la croissance et/ou la maturation de cellules Th1 ou Th2. Cette invention concerne également des compositions, des trousses et des méthodes destinées à détecter, caractériser, prévenir et traiter un état pathologique associé aux cellules Th1 ou Th2. Une pluralité de marqueurs sont utilisés, les changements de niveaux d'expression d'un ou de plusieurs de ces marqueurs étant liés à la présence d'une cellule Th1 ou Th2 ou d'un état pathologique associé aux cellules Th1 ou Th2.
Feldman Marc
Hanrahan Catherine F.
Trepicchio William L.
Bereskin & Parr
Feldman Marc
Genetics Institute Llc
Hanrahan Catherine F.
Kennedy Institute Of Rheumatology
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