Compositions, kits and methods for the diagnosis, prognosis,...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2737106

The present invention is based, in part, on the discovery that GOLPH3 plays a role in cancer, including lung, ovarian, pancreatic, liver, breast, prostate, and colon carcinomas, as well as melanoma and multiple myeloma. Accordingly, the invention relates to compositions, kits, and methods for diagnosing, prognosing, and monitoring cancer, e.g., lung, ovarian, pancreatic, liver, breast, prostate, and colon carcinomas, as well as melanoma and multiple myeloma.

La présente invention sappuie notamment sur la découverte que le GOLPH3 joue un rôle dans le cancer, y compris dans les carcinomes pulmonaires, ovariens, pancréatiques et hépatiques, les carcinomes de la poitrine, de la prostate et du colon, ainsi que dans le mélanome et le myélome multiple. En conséquence, l'invention porte sur des compositions, des kits et des procédés de diagnostic, de pronostic et de surveillance du cancer, par exemple des carcinomes pulmonaires, ovariens, pancréatiques et hépatiques, des carcinomes de la poitrine, de la prostate et du colon, ainsi que du mélanome et du myélome multiple.

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