Compositions, methods and devices for maintaining an organ

A - Human Necessities – 01 – N

Patent

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A01N 1/02 (2006.01) A61M 1/16 (2006.01)

Patent

CA 2304598

Compositions, methods, systems/devices and media are provided for maintaining a harvested organ in a functioning and viable state prior to implantation. The organ perfusion apparatus includes a preservation chamber for storing the organ during the preservation period. A perfusion circuit is provided having a first line for providing an oxygenated fluid to the organ, and a second line for carrying depleted fluid away from the organ. The perfusion apparatus also includes a device operably associated with the perfusion circuit for maintaining the organ at a substantially normothermic temperature.

Compositions, procédés, systèmes/dispositifs et supports utilisés pour conserver un organe prélevé dans un état viable et de fonctionnement avant son implantation. L'appareil de perfusion d'organes comprend une chambre de conservation permettant de stocker l'organe pendant la période de conservation. On utilise un circuit de perfusion comprenant une première ligne qui envoie un fluide oxygéné à l'organe et une deuxième ligne qui décharge l'organe du fluide appauvri. L'appareil de perfusion comprend également un dispositif associé au circuit de perfusion pour maintenir l'organe à une température sensiblement normothermique.

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