Compositions methods and systems for pulmonary delivery of...

Details Compositions methods and systems for pulmonary delivery of... Compositions methods and systems for pulmonary delivery of...

A - Human Necessities

61

K

A61K 38/21 (2006.01) A61K 9/12 (2006.01) A61K 31/70 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2484626

Stable aqueous formulations which are free of products derived from human or animal origin and which maintain high biological activity and high chemical and physical stability of alpha-type interferon for an extended period of time. Methods of producing stable aerosol formulations of the same for delivery to the lungs are also provided, as well as systems and methods of delivering the formulations to the lungs for systemic absorption.

L'invention concerne des formulations aqueuses stables qui sont exemptes de produits d~riv~s d'une origine humaine ou animale et qui conservent une activit~ biologique ~lev~e et une stabilit~ physique et chimique de l'interf~ron du type alpha pendant une p~riode prolong~e. L'invention concerne ~galement des proc~d~s permettant de produire des formulations d'a~rosol stables de celui-ci pour administration aux poumons, ainsi que des syst­mes et des proc~d~s d'administration de ces formulations aux poumons pour absorption syst­mique.

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