Compositions of alkylbenzenes in film-forming materials for...

A - Human Necessities – 61 – K

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A61K 49/04 (2006.01) C07C 17/12 (2006.01) C07C 17/26 (2006.01) C07C 17/354 (2006.01) C07C 25/02 (2006.01) C07C 69/65 (2006.01)

Patent

CA 2109443

ABSTRACT Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula Image and methods for their use in diagnostic radiology of the gastrointestinal tract wherein R = C1-C25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower- alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy- carbonyloxy, (CR1R2)p-(CR3=CR4)mQ, or (CR1R2)p-C?C-Q; R1, R2, R3 and R4 are independently H, lower-alkyl, optionally substituted with halo; n is 1-5; m is 1-5; p is 1-10; and Q is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.

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