Compositions of an orally active 1,2,4-oxadiazole for...

A - Human Necessities – 61 – K

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A61K 31/4245 (2006.01) A61P 3/10 (2006.01) A61P 7/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2603402

The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases associated with nonsense mutations. In particular, the invention relates to specific doses and dosing regimens for the use of 3-[5-(2-fluoro- phenyl)-[l,2,4]oxadiazol-3-yl]-benzoic acid in mammals having diseases associated with nonsense mutations.

La présente invention se rapporte à des doses et à des posologies spécifiques d'un composé d'acide 1,2,4-oxadiazole benzoïque, qui permettent de traiter ou de prévenir des maladies associées à des mutations non-sens. L'invention a trait en particulier à des doses et à des posologies spécifiques destinées à l'utilisation d'acide 3-[5-(2-fluoro-phényl)-[1,2,4]oxadiazol-3-yl]-benzoïque chez des mammifères atteints de maladies associées à des mutations non-sens.

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