Compositions of azimilide dihydrochloride

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) A61K 31/496 (2006.01) A61P 9/06 (2006.01)

Patent

CA 2672132

The present invention is directed to solvates and various polymorphic forms of (E)- 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4- imidazolidinedione dihydrochloride and pharmaceutical compositions thereof.

L'invention concerne des solvates et des formes polymorphes variées de dihydrochlorure de (E)- 1-[[[5-(4-chlorophényl)-2-furanyl]méthylène]amino]-3-[4-(4-méthyl-1-pipérazinyl)butyl]-2,4- imidazolidinedione et des compositions pharmaceutiques de ceux-ci.

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