A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 37/06 (2006.01) A61K 35/78 (2000.01)
Patent
CA 2372772
Method of treatment of lymphoproliferative and autoimmune disorders with a new composition of four boswellic acids including .beta.-boswellic acid, 3-O- acetyl-.beta.-boswellic acid, 11-keto-.beta.-boswellic acid, and 3-O-acetyl-11- keto-.beta.-boswellic acid. Boswellic acids of invention have been obtained in a novel industrial process from the gum resin of Boswellia serrata tree, providing standardized composition which inhibits DNA, RNA and protein synthesis of the target cell without cytotoxic effects. Composition of invention provides advantage of irreversible cytostatic therapy, equivalent to biological effects of a cytotoxic therapy without killing body cells.
L'invention concerne un procédé pour traiter des troubles lymphoprolifératifs et auto-immuns avec une nouvelle composition à base de quatre acides boswelliques comprenant l'acide .beta.-boswellique, 3-O-acétyl-.beta.-boswellique, 11-céto-.beta.-boswellique, et 3-O-acétyl-11-céto-.beta.-boswellique. On a obtenu les acides boswelliques de la présente invention par un nouveau procédé industriel à partir de la résine-gomme de l'arbre Boswellia serrata qui permet de créer une composition standardisée inhibant la synthèse d'ADN, d'ARN et de protéines de la cellule cible sans provoquer d'effets cytotoxiques. La composition de l'invention procure les avantages d'une thérapie cytostatique irréversible dont les effets biologiques équivalent à ceux d'une thérapie cytotoxique mais sans destruction de cellules du corps.
Badmaev Vladimir
Majeed Muhammed
Badmaev Vladimir
Majeed Muhammed
Sabinsa Corporation
Torys Llp
LandOfFree
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