Compositions of cholesteryl ester transfer protein...

Details Compositions of cholesteryl ester transfer protein... Compositions of cholesteryl ester transfer protein...

A - Human Necessities

61

K

A61K 31/138 (2006.01) A61K 9/18 (2006.01) A61K 31/40 (2006.01) A61K 31/4706 (2006.01) A61K 47/30 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2510458

A composition comprises (1) a solid amorphous adsorbate comprising a cholesteryl ester transfer protein (CETP) inhibitor and a substrate; and (2) an HMG-CoA reductase inhibitor. The solid amorphous adsorbate provides concentration enhancement of the CETP inhibitor relative to a control composition consisting essentially of the unadsorbed CETP inhibitor alone, resulting in improved bioavailability.

L'invention concerne une composition qui comprend : (1) un adsorbat amorphe solide comprenant un inhibiteur de la protéine de transfert du cholestérol estérifié (CETP) et un substrat ; et (2) un inhibiteur de l'HMG CoA-réductase. L'adsorbat amorphe solide assure le renforcement de la concentration de l'inhibiteur de la CETP par rapport à une composition témoin constituée essentiellement de l'inhibiteur de la CETP non adsorbé uniquement, ce qui améliore la biodisponibilité.

Affiliated with

Also associated with

Rating

Compositions of cholesteryl ester transfer protein... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions of cholesteryl ester transfer protein..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions of cholesteryl ester transfer protein... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2089093