Compositions of cpg and saponin adjuvants and methods thereof

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) C07H 15/24 (2006.01) C07H 21/00 (2006.01) C07J 17/00 (2006.01)

Patent

CA 2340174

Vaccine compositions of immunostimulatory oligonucleotides and saponin adjuvants and antigens and the use thereof for stimulating immunity, enhancing cell-mediated immunity, and enhancing antibody production are disclosed. Also described are immune adjuvant compositions comprising immunostimulatory oligonucleotides and saponin adjuvants, as well as methods for increasing an immune response using the same.

L'invention concerne des compositions de vaccin à base d'oligonucléotides immunostimulatoires, d'adjuvants à base de saponine, et d'antigènes, et leur utilisation pour stimuler l'immunité, améliorer l'immunité induite par une cellule, et améliorer la production d'anticorps. L'invention concerne également des compositions d'adjuvants immunitaires comprenant des oligonucléotides immunostimulatoires, et des adjuvants à base de saponine, ainsi que des procédés permettant de renforcer la réponse immunitaire au moyen de ces compositions.

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