Compositions of fgf-18 and hyaluronic acid for stimulating...

A - Human Necessities – 61 – K

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A61K 31/728 (2006.01) A61K 31/717 (2006.01) A61K 38/18 (2006.01) A61K 45/06 (2006.01) A61K 47/36 (2006.01) C07C 51/38 (2006.01) C07C 67/343 (2006.01) C07K 14/50 (2006.01)

Patent

CA 2500742

FGF18 is known to stimulate the proliferation of chondrocytes, resulting in increased cartilage formation. When hyaluronic acid is administered in addition to FGF18, the effects on chondrocyte proliferation and production of matrix were found to be greater than administration of FGF18 or hyaluronic acid alone.

FGF18 est connu pour stimuler la prolifération des chondrocytes, ce qui a pour conséquence d'augmenter la formation du cartilage. On a découvert que lorsqu'on administre de l'acide hyaluronique ajouté à FGF18, les effets sur la prolifération des chondrocytes et la production d'une matrice sont supérieurs que ceux obtenus par administration de FGF18 ou d'acide hyaluronique seul.

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