Compositions of hyaluronic acid and methods of use

A - Human Necessities – 61 – K

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Details

A61K 47/48 (2006.01) A61K 9/107 (2006.01) A61K 31/715 (2006.01) A61K 31/728 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2491054

The invention provides compositions for the treatment of disorders characterized by dryness including dry eye and dry mouth. The compositions commonly comprise a conjugate of hyaluronic acid and polylysine. These conjugates are attached to affected body tissues or surfaces using transglutaminase, and preferably endogenous transglutaminase.

L'invention porte sur des compositions destinées au traitement de troubles caractérisés par la sécheresse dont la sécheresse des yeux et de la bouche. Ces compositions contiennent généralement un conjugué d'acide hyaluronique et de polylysine. Ces conjugués sont fixés aux tissus ou surfaces du corps affectés au moyen de transglutaminase, et de préférence de transglutaminase endogène.

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