Compositions of n-(phosphonoacetyl)-l-aspartic acid and...

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01) A61K 31/70 (2006.01) A61K 38/21 (2006.01)

Patent

CA 2109435

Compositions and methods are disclosed which utilize the broad spectrum antiviral activity of PALA. This compound and its pharmaceutically acceptable analogs possess potent activity while displaying minimal toxicity and, therefore, are characterized by a relatively high therapeutic index. Compositions optionally containing other therapeutic agents, such as other antiviral agents, are also disclosed and are found to possess synergistic and/or additive antiviral activity.

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