Compositions of polypeptides specific to pathogenic strains...

Details Compositions of polypeptides specific to pathogenic strains... Compositions of polypeptides specific to pathogenic strains...

C - Chemistry, Metallurgy

07

K

C07K 14/245 (2006.01) A61K 39/108 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2559910

The invention relates to compositions of polypeptides specific to pathogenic strains comprising at least one polypeptide of a first group, having a sequence selected in the group comprising the sequences of SEQ ID N~ 159, or homologous sequences of polypeptides of the first group and/or the second group with a minimum of 25% of identity with the whole sequences of said polypeptides. Application for the preparation of vaccine compositions specific to E. coli extra-intestinal infections.

La présente invention a trait à des compositions de polypeptides spécifiques à des souches pathogènes comportant au moins un polypeptide d'un premier groupe, comprenant une séquence choisie dans le groupe constitué de SEQ ID N· 1 au N· 66 ou 133 145 et au moins un peptide d'un deuxième groupe comprenant la séquence SEQ ID N· 159, ou de séquences homologues de polypeptides du premier groupe et/ou du deuxième groupe avec un minimum de 25 % d'identité avec les séquences entières desdits polypeptides. L'invention est utile pour la préparation de compositions vaccinales spécifiques aux infections extra-intestinales liées à E. coli.

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