Compositions of semi-interpenetrating polymer network

C - Chemistry – Metallurgy – 08 – L

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C08L 5/08 (2006.01) A61L 27/26 (2006.01)

Patent

CA 2550906

Novel compositions consisting of semi-interpenetrating network of cross-linked water soluble derivatives of basic polysaccharides and a non-cross-linked component, which is an anionic polysaccharide are provided. Methods for the production of such compositions are also disclosed. Preferably the basic polysaccharide is chitosan or a derivative thereof and the anionic polysaccharide is hyaluronic acid. The compositions can be formed into gels or films, for example, and thus find use in a wide range of medical applications in the fields of dermatology, plastic surgery, urology and orthopaedics.

L'invention concerne de nouvelles compositions constituées d'un réseau semi-interpénétrant de dérivés hydrosolubles polymérisés de polysaccharides de base, et un composant non réticulé, qui est un polysaccharide anionique. L'invention concerne aussi des procédés de fabrication de ces compositions. De préférence, le polysaccharide de base est un chitosane ou son dérivé, et le polysaccharide anionique est un acide hyaluronique. Les compositions peuvent avoir la forme de gels ou de films et, de ce fait, s'utiliser dans une vaste gamme d'applications médicales, dans les domaines de dermatologie, de chirurgie plastique, d'urologie et d'orthopédie.

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