Compositions of solvents and high concentrations of nucleic...

Details Compositions of solvents and high concentrations of nucleic... Compositions of solvents and high concentrations of nucleic...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2372036

The invention provides compositions and methods suitable for dissolving nucleic acid analogs with uncharged, neutral backbones at high concentrations at approximately neutral pH. By using the compositions of the invention, which include a polar, aprotic solvent, concentrations of nucleic acid analogs such as PNA can be achieved in the range of approximately 1 µM to 10 mM.

La présente invention concerne des compositions et des procédés aptes à dissoudre des analogues d'acide nucléique à squelettes neutres et non chargés à concentrations élevées et à pH plus ou moins neutre. Par l'utilisation des compositions selon l'invention, qui comprennent un solvant polaire aprotique, on peut obtenir des concentrations d'analogues d'acide nucléique telle la protéine PNA dans une plage d'environ 1µM à 10 mM.

Affiliated with

Also associated with

Rating

Compositions of solvents and high concentrations of nucleic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions of solvents and high concentrations of nucleic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions of solvents and high concentrations of nucleic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2077400