Compositions suitable for controlled release of the hormone...

Details Compositions suitable for controlled release of the hormone... Compositions suitable for controlled release of the hormone...

A - Human Necessities

61

K

A61K 38/09 (2006.01) A61K 9/08 (2006.01) A61P 15/08 (2006.01)

Patent

CA 2291087

A liquid composition for the controlled release of gonodotropin releasing hormone (GnRH) or its analogs is provided that includes: (i) a non-polymeric, non-water soluble liquid carrier material (HVLCM) or viscosity of at least 5,000 cP at 37 °C that does not crystallize neat under ambient or physiological conditions; and (ii) GnRH or analogs thereof.

L'invention concerne une composition liquide assurant la libération régulée d'une hormone libérant de la gonadolibérine (GnRH), ou de ses analogues, laquelle composition contient: (i) un excipient liquide non soluble dans l'eau et non polymère qui possède une viscosité au moins égale à 5 000 cP à 37 DEG C, et qui ne se cristallise pas nettement sous des conditions ambiantes ou physiologiques; et (ii) la GnRH ou des analogues de celle-ci.

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