Compositions, systems, and methods for creating in situ,...

Details Compositions, systems, and methods for creating in situ,... Compositions, systems, and methods for creating in situ,...

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61B 17/00 (2006.01)

Patent

CA 2340648

A biocompatible and biodegradable material is applied to a tissue region, e.g., to seal a vascular puncture site, or to arrest the flow of blood or fluid from body tissue, or to arrest diffuse bleeding. The material preferably includes a protein comprising recombinant or natural serum albumin, which is mixed with a polymer that comprises poly(ethylene) glycol (PEG), and, most preferably, a multi-armed PEG polymer.

L'invention concerne une matière biocompatible et biodégradable qui s'applique sur une zone de tissu, p. ex. pour obturer un site de perforation vasculaire, ou pour arrêter l'écoulement de sang ou de fluide provenant du tissu corporel, ou pour arrêter un saignement diffus. La matière renferme de préférence une protéine comportant de l'albumine de sérum naturelle ou recombinée, qui est mélangée à un polymère contenant du poly(éthylène) glycol (PEG) et, idéalement, un polymère de PEG à bras multiples.

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