Compositions that soften at predeterminded temperatures and...

A - Human Necessities – 61 – M

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400/1, 400/1301,

A61M 25/00 (2006.01) B29C 35/16 (2006.01) C08F 20/04 (2006.01)

Patent

CA 1278123

ABSTRACT The present invention provides a composition that softens at a predetermined temperature between about 20°C and about 62°C, comprising at least one block copolymer having at least two thermal transition temperatures. The composition is characterized by at least two thermal transition temperatures, one of which is a predetermined lower transition temperature between about 20°C to about 62°C and one of which is an upper transition temperature above about 62°C. The composition has the physical properties of a rigid, crystalline or glassy polymer below the predetermined transition temperature and the physical properties of a flexible, rubbery polymer at and above the predetermined transition temperature, but below the upper transition temperature. In a preferred embodi- ment, the composition of the present invention further comprises a plasticizer or polymer that has at least one thermal transition temperature and is thermodynamically compatible with at least one block of the block copoly- mer. For most biomedical applications, the composition of the present invention has a predetermined glass transition temperature at or near body temperature. The present invention also provides a method of making the composition, a method of making biomedical devices and materials and articles with shape-memory properties from the composition, and biomedical devices and materials and articles with shape-memory properties made from the composition.

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