Compositions useful as fibrin sealants

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/14 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/48 (2006.01) A61L 24/10 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2293499

Novel fibrin monomer compositions which are solutions including additional coharvested components, such as prothrombin and Factor XIII, are useful in fibrin sealant applications. Preferably, the compositions are autologous to the patient receiving the sealant and these compositions may also include coharvested plasminogen, Factor X, antithrombin III and/or fibronectin.

L'invention concerne de nouvelles compositions de monomère de fibrine, lesquelles sont des solutions contenant des constituants additionnels coprélevés, tels que la prothrombine et le facteur XIII, lesquelles sont utiles dans des applications d'agents de scellement à base de fibrine. De préférence, les compositions sont autologues au patient recevant l'agent de scellement et ces compositions peuvent également comprendre du plasminogène, le facteur X, de l'anti-thrombine III et/ou de la fibronectine coprélevés.

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