Compositions useful as inhibitors of rock and other protein...

Details Compositions useful as inhibitors of rock and other protein... Compositions useful as inhibitors of rock and other protein...

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2504320

The present invention relates to substitute thiazole and thiophene derivatives useful as inhibitors of rock and other protein kinaeses. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders, including proliferative, cardiac and neurodegenerative diseases.

L'invention concerne des dérivés thiazole et thiophène substitués utiles en tant qu'inhibiteurs de rock et d'autres protéines kinases. L'invention concerne également des compositions pharmaceutiquement acceptables comprenant lesdits composés, et des méthodes d'utilisation de ces compositions pour le traitement de maladies, d'états pathologiques ou de troubles variés, notamment des maladies prolifératives, cardiaques et neurodégénératives.

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