Compositions useful for the treatment of diabetes and other...

A - Human Necessities – 61 – K

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A61K 38/28 (2006.01)

Patent

CA 2720864

The present invention provides a supramolecular protein assembly useful as a protein therapeutics for the treatment of metabolic disorders particularly diabetes. The supramolecular protein assembly disclosed in the present invention consists of insoluble and aggregated oligomers the protein. The invention also provides pharmaceutical compositions comprising supramolecular protein assembly. The composition disclosed in the present invention particularly comprises supramolecular insulin assembly.

La présente invention porte sur un assemblage supramoléculaire de protéine utile comme produit thérapeutique à base de protéine dans le traitement de troubles métaboliques, en particulier du diabète. L'assemblage supramoléculaire de protéine décrit dans la présente invention renferme des oligomères insolubles et des agrégés de la protéine. La présente invention porte également sur des compositions pharmaceutiques comprenant un assemblage supramoléculaire de protéine et, en particulier, sur un assemblage supramoléculaire d'insuline.

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