Compositions useful for transferring therapeutically active...

Details Compositions useful for transferring therapeutically active... Compositions useful for transferring therapeutically active...

A - Human Necessities

61

K

A61K 47/20 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 47/16 (2006.01) A61K 47/22 (2006.01) A61K 48/00 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2242035

The present invention relates to a composition which is intended for transferring at least one therapeutically active substance into the interior of a target cell, characterized in that it comprises a mixture of at least one therapeutically active substance and at least one polar compound which is selected from a specific group of aprotic polar compounds. The therapeutically active substance is preferably a polynucleotide, and the polar compound is DPSO, which improves the ability of the polynucleotide to be transfected into the interior of the cells. The compositions according to the invention can be used as a diagnostic therapeutic, prophylactic or vaccinal medicament for treating the human or animal body by means of gene therapy.

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