Compositions useful in gene therapy

A - Human Necessities – 61 – K

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Details

A61K 47/48 (2006.01) A61K 47/42 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01) C12N 15/87 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2439315

The present invention relates to the use of non-complexing peptides for the preparation of compositions useful for improving transfer of substances of interest into cells. Such compositions are specially useful in gene therapy, vaccination, and any therapeutic or prophylactic situation in which a substance of interest, particularly a nucleic acid is administered to cells in vivo.

L'invention concerne l'utilisation de peptides non complexants pour préparer des compositions permettant d'améliorer le transfert de substances d'intérêt dans des cellules. De telles compositions sont particulièrement utiles en thérapie génique, en vaccination et en toute situation thérapeutique ou prophylactique dans laquelle une substance d'intérêt, notamment un acide nucléique, est administrée à des cellules in vivo.

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