Compositions which inhibit apoptosis, methods of purifying...

A - Human Necessities – 61 – K

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A61K 36/88 (2006.01) C12N 5/07 (2010.01) A01N 1/02 (2006.01) A61K 36/48 (2006.01) A61K 36/81 (2006.01) A61K 47/00 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 43/00 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2177825

The present invention is directed to methods of obtaining plant-derived delip- idated extracts that inhibit apoptosis, the extracts obtained, compositions containing said extracts and methods of using said com- positions. The figure is a bar graph which illustrates a lower incidence of diarrhea in rats treated with methotrexate and fed a diet of compositions of the claimed invention as compared to controls.

L'invention concerne des procédés de production d'extraits délipidés dérivés de végétaux inhibant l'apoptose, les extraits ainsi obtenus, des compositions contenant lesdits extraits et des procédés d'utilisation de ces dernières. La figure représente un diagramme en bâtons montrant que l'incidence de la diarrhée est moindre chez les rats traités avec du méthotrexate et nourris avec les compositions de l'invention.

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