Compositions with reduced dimer formation

Details Compositions with reduced dimer formation Compositions with reduced dimer formation

A - Human Necessities

61

K

A61K 9/19 (2006.01) A61K 39/35 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2744587

The present invention relates to the use of a non-reducing carbohydrate or carbohydrate derivative and at least one agent which inhibits dimer formation in a freeze-dried composition comprising at least one peptide that contains a free cysteine residue, to provide a freeze-dried composition with improved long-term storage stability.

La présente invention concerne l'utilisation de glucides non réducteurs ou de dérivés de glucides non réducteurs et d'au moins un agent qui empêche la formation de dimères dans une composition lyophilisée comprenant au moins un peptide qui contient un résidu de cystéine libre, de façon à donner une composition lyophilisée dont la stabilité au stockage de longue durée est accrue.

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