Compound - 946

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/14 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2692725

A compound of formula (I) or a pharamaceutically acceptable salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use intherapy, for example in the treatment of proliferative disease such as cancer and particularly in disease mediated by an mTOR kinase and/or one or more PI3K enzyme.

L'invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, leurs procédés de préparation, les compositions pharmaceutiques les contenant et leur utilisation en thérapie, par exemple, dans le traitement de maladies prolifératives telles que le cancer et, notamment, de maladies induites par une kinase mTOR et/ou une ou plusieurs enzymes PI3K.

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