A - Human Necessities – 61 – N
Patent
A - Human Necessities
61
N
A61N 1/30 (2006.01) A61M 37/00 (2006.01) A61N 1/32 (2006.01) A61B 17/00 (2006.01)
Patent
CA 2272647
A method for delivering compounds through epithelial cell layers using impulse transients is described. The method involves applying a compound to, e.g., the stratum corneum, of a patient and then inducing impulse transients to create transient increases in the permeability of epithelial tissue, thereby facilitating delivery of the compound across the epithelial cell layer.
L'invention concerne un procédé d'apport de composés, à travers les couches de cellules épithéliales, faisant appel à des phénomènes transitoires. Le procédé consiste à appliquer un composé sur, par exemple, la couche cornée de la peau d'un patient, puis à provoquer des phénomènes transitoires impulsionnels de manière à augmenter, de façon transitoire, la perméabilité de l'épithélium, ce qui facilite l'apport du composé à travers la couche de cellules épithéliales.
Doukas Apostolos G.
Flotte Thomas J.
Kollias Nikiforos
Lee Shun K.
Mcauliffe Daniel J.
Smart & Biggar
The General Hospital Corporation
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