C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/097 (2006.01) A61K 38/06 (2006.01) A61P 29/00 (2006.01) C07K 5/08 (2006.01) C07K 14/00 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2364512
The invention relates to a compound suitable for inhibiting the influx of polymorphonuclear leukocytes (PMNs) into a tissue involved in a chronic inflammatory disease. The compound according to the invention is capable of forming a complex with N-acetyl-Pro-Gly-Pro. The invention also relates to a method of selecting such a compound, a pharmaceutical composition and an application of the compound.
L'invention concerne un composé pouvant être utilisé pour inhiber l'invasion de leucocytes polymorphonucléaires (PMN) dans un tissu responsable d'une maladie inflammatoire chronique. Le composé de la présente invention est capable de former un complexe avec N-acétyl-Pro-Gly-Pro. L'invention concerne également un procédé de sélection d'un tel composé, une composition pharmaceutique et une application du composé.
Blalock James Edwin
Haddox Jeffrey Lynn
Nijkamp Franciscus Petrus
Pfister Rosswell Robert
Villain Matteo
Borden Ladner Gervais Llp
Fornix Biosciences N.v.
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