Compound inducing angiogenesis response in ischaemic tissues

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 229/26 (2006.01) A61K 31/198 (2006.01) C07C 227/14 (2006.01)

Patent

CA 2709553

This invention deals with a novel straight chain compound, namely, 1,6-diamino alkanoic acid having a straight chain of six carbon atoms with two terminal amino groups and accompanying - COOH group, which is capable of effecting controlled formation of new blood vessels in ischaemic tissues, and their pharmaceutically acceptable salts and/or derivatives thereof. The compounds may be in laevo, dextro, activated laevo, activated dextro or oligomeric form. The invention also pertains to a process for preparing the aforesaid novel compound, which is illustrated by the accompanying drawing.

L'invention porte sur un nouveau composé à chaîne linéaire, à savoir un acide 1,6-diamino alcanoïque possédant une chaîne linéaire de six atomes de carbone avec deux groupes amine terminaux et un groupe d'accompagnement -COOH, lequel composé permet d'entraîner la formation contrôlée de nouveaux vaisseaux sanguins dans les tissus ischémiques; et sur des sels et/ou dérivés pharmaceutiquement acceptables de ce dernier. Lesdits composés peuvent se présenter sous la forme laevo, dextro, laevo activée, dextro activée ou oligomère. L'invention se rapporte également à un procédé de préparation du nouveau composé précité, qui est illustré dans la figure annexe.

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