Compound inhibiting presenilin 1 for preparing a medicine...

Details Compound inhibiting presenilin 1 for preparing a medicine... Compound inhibiting presenilin 1 for preparing a medicine...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/70 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2304011

The invention concerns a compound inhibiting: a) the cellular expression of a nucleotide sequence corresponding to all or part of the gene of Presenilin 1, or b) the cellular expression of a nucleotide sequence having at least 90 % homology with a nucleotide sequence as per a), or c) the action of a product for expression of a sequence as per a) or b), for preparing a medicine. The invention also concerns diagnostic agents for detecting and monitoring said diseases.

L'invention concerne un composé assurant l'inhibition: a) de l'expression cellulaire d'une séquence nucléotidique correspondant à tout ou partie du gène de la Préséniline 1, ou b) de l'expression cellulaire d'une séquence nucléotidique présentant au moins 90 % d'homologie avec une séquence nucléotidique selon a), ou c) de l'action du produit d'expression d'une séquence selon a) ou b), pour la préparation d'un médicament. Elle concerne également des agents de diagnostic pour la détermination et le suivi de ces maladies.

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