C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 31/165 (2006.01) A61K 31/704 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 7/02 (2006.01)
Patent
CA 2741475
The present invention relates to prodrugs of vascular disrupting agents comprising a vascular disrupting agent (VDA) associated with a MMP proteolytic cleavage site and to the use of such prodrugs in the targeted treatment of cancer.
Linvention concerne des promédicaments dagents de destruction vasculaire comprenant un agent de destruction vasculaire (VDA) associé à un site de clivage protéolytique MMP, et lutilisation de ces promédicaments dans le traitement ciblé du cancer.
Atkinson Jennifer
Bibby Michael
Falconer Robert Andrew
Gill Jason
Loadman Paul
Ridout & Maybee Llp
University Of Bradford
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