Compounds

Details Compounds Compounds

C - Chemistry, Metallurgy

07

K

167/103.05, 530/

C07K 5/04 (2006.01) A61K 38/04 (2006.01) C07F 9/38 (2006.01) C07F 9/40 (2006.01) C07F 9/553 (2006.01) C07F 9/572 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01)

Patent

CA 2014375

B2722/Abs Abstract Novel compounds of formula (I) and salts, solvates and hydrates thereof, processes for their preparation and their use in the treatment of conditions in which degradation of connective tissue and other proteinaceous components of the body occurs: Image (I) in which, R is hydrogen, C1-6 alkyl or optionally substituted benzyl; R1 is hydrogen or C1-6 alkyl; R2 is C3-6 alkyl; R3 is hydrogen, alkyl, -CH2-Z where z is optionally substituted phenyl or heteroaryl, or R3 is a group Image where R7 is hydrogen, alkyl or -CH2-Ph where Ph is optionally substituted phenyl and R8 is hydrogen or alkyl; and R4 is -CH2-(CH2)nOR5 or -CH2-(CH2)nOCOR6 or -CH(R9)COR10, where n is an integer from 1 to 6; R5, R6 and R9 are hydrogen or C1-6 alkyl; and R10 is hydroxy or -O-C1-6 alkyl or -NR5R6 (where R5 and R6 may be linked to form a heterocyclic ring; or R3 and R4 are joined together as -(CH2)m- where m is an integer from 4 to 12.

Affiliated with

Also associated with

Rating

Compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1550186