Compounds

Details Compounds Compounds

C - Chemistry, Metallurgy

07

D

C07D 407/04 (2006.01) A61K 31/11 (2006.01) A61K 31/12 (2006.01) A61K 31/235 (2006.01) A61K 31/375 (2006.01) C07B 59/00 (2006.01) C07C 47/544 (2006.01) C07C 49/86 (2006.01) C07C 69/76 (2006.01) C07C 235/84 (2006.01) C07C 255/56 (2006.01) C07D 339/06 (2006.01)

Patent

CA 2087651

Abstract New compounds of formula I: Image (I) wherein Y may be CN or Image wherein A may be H, D, alkyl with 1-4 carbon atoms, OR wherein R is H or alkyl with 1-4 carbon atoms, or-NR1R2 or-CR1R2R3 wherein R1, R2 and R3 are the same or different and are H or alkyl with 1-4 carbon atoms; Z is H, D, Y or alkyl with 1-4 C-atoms, halogen, nitro, amino, monoalkyl amino or dialkyl amino wherein the alkyl groups have 1-4 C atoms, or-OR wherein R may be H or alkyl with 1-4 C-atoms, or-CR4R5R6 wherein R4 R5 and R6 may be the same or different and may be H or F; and pharmaceutically acceptable salts thereof. are useful as anti-cancer agents or as intermediates for preparing anti-cancer agents.

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