Compounds

Details Compounds Compounds

C - Chemistry, Metallurgy

07

D

167/240, 260/321

C07D 209/54 (2006.01) A61K 31/40 (2006.01) C07D 209/96 (2006.01) C07D 487/10 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2035966

ABSTRACT The present invention relates to spiroisoindolines that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.

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