C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/250, 260/457
C07F 9/40 (2006.01) A61K 31/665 (2006.01) C07F 9/547 (2006.01)
Patent
CA 2025268
22003/4 ABSTRACT COMPOUNDS Compounds of structure (I) Image (I) in which: B is Image or Image where R is hydrogen or C1-4alkyl and q is 0 or 1; R1 is hydrogen or C1-4alkyl; R2, R3, R4 and R5 are the same or different and are OR7 in which R7 is hydrogen or C1-8alkyl; or R2 and R3 together and R4 and R5 together form a C2-8alkylene dioxy ring; R6 is hydrogen or C1-4alkyl; m is 0 or 1, and A is S, S(CH2)n, CH?CHCH2, (CH2)n or (CH=CH)p(CH2)tCH= in which n is 1 to 7, p is 0 or 1 and t is 0 to 4, with the proviso that m is 0 only when A is (CH=CH)p(CH2)tCH=, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as antihyperlipidaemic agents.
Kruse Lawrence Ivan
Shah Virendra Premchand
Gowling Lafleur Henderson Llp
Symphar S.a.
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