Compounds

Details Compounds Compounds

C - Chemistry, Metallurgy

07

D

167/228, 260/270

C07D 451/04 (2006.01) A61K 31/445 (2006.01) C07D 453/02 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2027093

- 1 - Abstact Novel Compounds A compound of formula (I) or a pharmaceutically acceptable salt thereof: Image (I) in which one of X and Y represents hydrogen and the other represents Z, where Z is a group Image in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises zero, one or two nitrogen atoms, Q being optionally C-substituted by a group R1 selected from halogen, CN, OR2, SR2, N(R2)2, NHCOR2, NHCOOCH3, NHCOOC2H5, NHOR2, N3, NHNH2, NO2, COR2, COR3, C2-4 alkenyl, C2-4 alkynyl, cyclopropyl or C1-2 alkyl optionally substituted with OR2, N(R2)2, SR2, CO2R2, CON(R2)2 or one, two or three halogen atoms, in which each R2 is independently hydrogen or C1-2 alkyl and R3 is OR2, NH2 or NHR2; r represents an integer of 2 or 3, s represents an integer of 1 or 2 and t represents 0 or 1; Ra and Rb each represent hydrogen or, when X is hydrogen, optionally together represent a bond; with the proviso that when Y is hydrogen s is 1.

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