Compounds

Details Compounds Compounds

C - Chemistry, Metallurgy

07

D

167/228, 260/270

C07D 453/02 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07D 471/08 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2000042

Novel Compounds Abstract A compound of formula (I) or a pharmaceutically acceptable salt thereof: Image (I) in which one of X and Y represents hydrogen and the other represents -CH2-Z where Z is a group Image in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being optionally substituted by a C1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R1; or a group Image in which A1, A2 and A3 complete a 5-membered aromatic ring and A1 is oxygen or sulphur, one of A2 and A3 is CR2 and the other is nitrogen or CR3, or A2 is oxygen or sulphur, one of A1 and A3 is CR2 and the other is CR3; and R1, R2 and R3 are independently selected from hydrogen, halogen, CN, OR4, SR4, N(R4)2, NHCOR4, NHCOOCH3, NHCOOC2H5, NHOR4, NHNH2, NO2, COR4, COR5, C2-4 alkenyl, C2-4 alkynyl, cyclopropyl or C1-2 alkyl optionally substituted with OR4, N(R4)2, SR4, CO2R4, CON(R4)2 or one, two or three halogen atoms, in which each R4 is independently hydrogen or C1-2 alkyl and R5 is OR4, NH2 or NHR4; r represents an integer of 2 or 3, s represents an integer of 1 or 2 and t represents 0 or 1, with the proviso that when Y is hydrogen s is 1.

Affiliated with

Also associated with

Rating

Compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2076353