Compounds active at a novel site on receptor-operated...

Details Compounds active at a novel site on receptor-operated... Compounds active at a novel site on receptor-operated...

C - Chemistry, Metallurgy

07

C

C07C 211/26 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2560002

Disclosed is a novel compound of the formula: (see formula I or II) in which W is CH2, O or S; X1 and X2 are F, Cl, CH3, OH or alkoxy; 2 is CH2CH2, CH2CH (CH3) , CH=CH, O or S; R is H, CH3 or C2H5; R1 is H, alkyl, hydroxyalkyl, OH, alkoxy or acyloxy; R2 is H, alkyl or hydroxyalkyl; and m is 0, 1 or 2, which is active at an NMDA receptor and is useful as neuroprotectant, anticonvulsant, anxiolytic, analgesic, muscle relaxant, adjuvant to general anesthetic or the like.

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