Compounds active at a novel site on receptor-operated...

Details Compounds active at a novel site on receptor-operated... Compounds active at a novel site on receptor-operated...

C - Chemistry, Metallurgy

07

C

C07C 211/27 (2006.01) A61K 31/135 (2006.01) A61K 31/335 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07C 211/28 (2006.01) C07C 211/29 (2006.01) C07C 211/40 (2006.01) C07C 215/28 (2006.01) C07C 215/54 (2006.01) C07C 217/10 (2006.01) C07C 217/62 (2006.01) C07C 219/22 (2006.01) C07C 257/14 (2006.01) C07C 323/32 (2006.01) C07D 207/08 (2006.01) C07D 207/12 (2006.01) C07D 211/18 (2006.01) C07D 213/38 (2006.01) C07D 311/90 (2006.01) C07D 313/12 (2006.01) C07D 333/

Patent

CA 2257234

Method and compositions for treating a patient having a neurological disease or disorder, such as stroke, head trauma, spinal cord injury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage, epilepsy, anxiety, neuropsychiatric or cognitive deficits due to ischemia or hypoxia such as those that frequently occur as a consequence of cardiac surgery under cardiopulmonary bypass, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Disease, Parkinson's Disease, or amyotrophic lateral sclerosis (ALS).

Procédé et compositions servant à traiter un malade atteint d'une maladie ou de troubles neurologiques, tels qu'une attaque, un traumatisme crânien, une lésion de la moelle épinière, l'ischémie de la moelle épinière, la détérioration des cellules nerveuses provoquée par l'ischémie ou par l'hypoxie, l'épilepsie, l'anxiété, des déficiences neuropsychiatriques ou cognitives dues à l'ischémie ou à l'hypoxie, telles que celles qui apparaissent fréquemment à la suite d'une chirurgie cardiaque sous circulation extra-corporelle, ou des maladies neurodégénératives, telles que la maladie d'Alzheimer, la maladie de Huntington, la maladie de Parkinson ou la sclérose latérale amyotrophique.

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