C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/08 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2651762
The invention provides compounds of formula (1) and pharmaceutically acceptable salts, hydrates, solvates, stereoisomers and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP- 1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
L'invention concerne des composés et des compositions pharmaceutiques issues de ces composés convenant pour la modulation de protéases activatrices de canal, ainsi que des méthodes d'utilisation de tels composés pour le traitement, l'amélioration ou la prévention d'un état pathologique associé à des protéases activatrices de canal dont la liste non limitative comprend la prostasine, PRSS22, TMPRSS11 (telles que TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsine, cathepsine A, ou élastase neutrophile.
Bursulaya Badry
Chatterjee Arnab K.
Petrassi Hank Michael James
Spraggon Glen
Tully David C.
Fetherstonhaugh & Co.
Irm Llc
LandOfFree
Compounds and compositions as channel activating protease... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds and compositions as channel activating protease..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and compositions as channel activating protease... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1693346