Compounds and compositions as itpkb inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61P 17/00 (2006.01) A61P 19/02 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/14 (2006.01) C07D 491/048 (2006.01)

Patent

CA 2656715

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated B cell activities, particularly diseases or disorders that involve aberrant activation of inositol 1, 4, 5-trisphosphate 3-kinase B (ITPKb).

La présente invention concerne une nouvelle classe de composés, des compositions pharmaceutiques contenant de tels composés et des procédés d'utilisation de tels composés pour traiter ou prévenir des maladies ou des troubles associés à des activités anormales ou déréglées des lymphocytes B, en particulier des maladies ou des troubles qui impliquent une activation aberrante de l'inositol 1,4,5-trisphosphate 3-kinase B (ITPKb).

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