Compounds and compositions as kinase inhibitors

Details Compounds and compositions as kinase inhibitors Compounds and compositions as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2672101

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly TrkA, TrkB, TrkC, PDGFR and c-kit.

L'invention concerne une nouvelle classe de composés, des compositions pharmaceutiques comprenant de tels composés et des procédés d'utilisation de tels composés pour traiter et prévenir des maladies ou des troubles associés à une activité kinase anormale ou déréglée, en particulier trkA, trkB, trkC, PDGFR et c-kit.

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