C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/4178 (2006.01)
Patent
CA 2567662
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, SGK, Tie2, Lck, JNK2 2, MKK4, c-RAF, MKK6, SAPK2 and SAPK2 kinases.
L'invention concerne une nouvelle classe de composés, des compositions pharmaceutiques comprenant ces composés et des méthodes d'utilisation desdits composés pour traiter ou prévenir des maladies ou des troubles associés à une activité kinase anormale ou déréglée, et notamment les maladies ou les troubles caractérisés par une activation anormale des kinases Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, SGK, Tie2, Lck, JNK2 2, MKK4, c-RAF, MKK6, SAPK2 et SAPK2.
Albaugh Pamela A.
Chopiuk Greg
Ding Qiang
Gray Nathanael Schiander
Ren Pingda
Fetherstonhaugh & Co.
Irm Llc
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