C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2607299
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of Abl, Bcr-Abl, Bmx, BTK, b-RAF, c RAF, CSK, cSRC, Fes, FGFR3, Flt3, IKK.alpha., IKK.beta., JNK1.alpha.1, JNK2.alpha.2, Lck, Met, MKK4, MKK6, p70S6K, PAK2, PDGFR.alpha., PKA, PKC.alpha., PKD2, ROCK-II, Ros, Rsk1, SAPK2.alpha., SAPK2.beta., SAPK3, SAPK4, SGK, Syk, Tie2 and TrkB kinases.
La présente invention concerne une nouvelle classe de composés, des compositions pharmaceutiques ) base de tels composés, et des procédés d'utilisation thérapeutique ou prophylactique de tels composés contre des affections ou troubles associés à une activité kinase anormale ou dérégulée, notamment des affections ou troubles impliquant une activation anormale des Abl, Bcr-Abl, Bmx, BTK, b-RAF, c RAF, CSK, cSRC, Fes, FGFR3, Flt3, IKKa, IKKß, JNK1a1, JNK2a2, Lck, Met, MKK4, MKK6, p70S6K, PAK2, PDGFRa, PKA, PKCa, PKD2, ROCK-II, Ros, Rsk1, SAPK2a, SAPK2ß, SAPK3, SAPK4, SGK, Syk, Tie2 et TrkB kinases.
Gray Nathanael Schiander
Liu Yi
Nagle Advait
Ren Pingda
Sim Taebo
Fetherstonhaugh & Co.
Irm Llc
LandOfFree
Compounds and compositions as protein kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds and compositions as protein kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and compositions as protein kinase inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1741200