Compounds and compositions useful as cathepsin s inhibitors

Details Compounds and compositions useful as cathepsin s inhibitors Compounds and compositions useful as cathepsin s inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/506 (2006.01) A61P 25/02 (2006.01) C07D 401/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2575826

The present invention relates to the use of a 2-cyanopyrimidine compound of the formula (I), wherein R1, R2, R3 and X are as defined in the specification and in the claims, in free form or in salt form, and , where possible, in tautomeric form, as an inhibitor of the activity of cathepsin S.

L'invention concerne un composé de 2-cyanopyrimidine représenté par la formule (I), dans laquelle R1, R2, R3 et X sont tels que définis dans la spécification et les revendications, sous forme libre ou sous forme de sel, et lorsque c'est possible, sous forme tautomère, utilisé comme inhibiteur de l'activité de la cathepsine S.

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