Compounds and conjugates

Details Compounds and conjugates Compounds and conjugates

C - Chemistry, Metallurgy

12

N

C12N 9/96 (2006.01) A61K 47/48 (2006.01) C07D 207/416 (2006.01) C12N 11/00 (2006.01) G01N 33/531 (2006.01) G01N 33/535 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2101734

-26- NOVEL COMPOUNDS AND CONJUGATES ABSTRACT OF THE DISCLOSURE A compound represented by the formula Image wherein X is a spacer group. The compound is useful for conjugating a compound having an alcohol group or an amine group to a compound having a thiol group. The compound can be used to conjugate a biologically active group such as an antigen to a protein such as an enzyme to provide an enzyme-labeled antigen for use in enzyme - amplified immunoassay methods for analytes or metabolites in sample fluids. The compound can also be used to immobilize a material such as a protein to a solid support.

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