C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/22 (2006.01) A61K 31/198 (2006.01) A61K 31/405 (2006.01) A61K 31/41 (2006.01) A61K 31/4172 (2006.01) A61K 31/4406 (2006.01) A61K 31/662 (2006.01) A61P 29/00 (2006.01) C07C 233/51 (2006.01) C07C 235/12 (2006.01) C07C 237/16 (2006.01) C07C 271/22 (2006.01) C07D 209/20 (2006.01) C07D 213/30 (2006.01) C07D 213/55 (2006.01) C07D 213/56 (2006.01) C07D 233/26 (2006.01) C07D 233/54 (2006.01) C07D 257/04 (2006.01) C07F 9/40 (2006.01)
Patent
CA 2417127
The present invention relates generally to amino acid derivatives and to methods of making the same. In particular, the invention relates to compounds bearing a stereochemical identity, that is, the same stereochemistry, with the chiral .alpha.-carbon of D-.alpha.-amino acids and their use in methods of therapy, including the treatment of inflammatory diseases, and to compositions and enantiomeric mixtures containing them.
L'invention concerne d'une manière générale des dérivés d'acides aminés ainsi que des procédés permettant de les produire. En particulier, l'invention concerne des composés portant une identité stéréochimique, à savoir la même stéréochimie, avec le carbone-.alpha. chiral des acides aminés-.alpha.-D, et leur utilisation dans des procédés thérapeutiques, y compris le traitement de maladies inflammatoires. Elle concerne également des compositions et des mélanges énantiomères renfermant ces composés.
Clark Christopher I.
Fairlie David P.
Hansford Karl
Mcgeary Ross P.
Reid Robert C.
Fetherstonhaugh & Co.
The University Of Queensland
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