C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/04 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) C07K 14/35 (2006.01) C07K 19/00 (2006.01) C12N 1/19 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01) G01N 33/60 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2268008
Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
L'invention concerne des composés et des méthodes destinés à induire une immunité contre la tuberculose. Ces composés comprennent des polypeptides qui contiennent au moins une partie immunogène d'une ou plusieurs protéines de M. tuberculosis et des molécules d'ADN codant ces polypeptides. De tels composés peuvent être préparés sous forme de vaccins et/ou de compositions pharmaceutiques qui servent à immuniser un patient contre une infection provoquée par M. tuberculosis ou à diagnostiquer la tuberculose.
Campos-Neto Antonio
Dillon Davin C.
Houghton Raymond
Lodes Michael J.
Reed Steven G.
Corixa Corporation
Osler Hoskin & Harcourt Llp
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