Compounds and methods for inhibiting propagation of human...

Details Compounds and methods for inhibiting propagation of human... Compounds and methods for inhibiting propagation of human...

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2194398

The present invention concerns the use of oligonucleotides to inhibit propagation of human immunodeficiency virus (HIV). Preferred HIV target sites are identified and oligonucleotides designed to hybridize to a target site, or be analogous to a target site, are described. The preferred use of the oligonucleotides is to inhibit HIV propagation in a patient infected with HIV.

La présente invention concerne l'utilisation d'oligonucléotides pour inhiber la propagation du virus de l'immunodéficience humaine (VIH). Des sites cibles préférés de VIH sont identifiés et des oligonucléotides conçus pour s'hybrider avec un site cible, ou former un analogue d'un site cible, sont décrits. On utilise, de préférence, ces oligonucléotides pour inhiber la propagation du VIH chez un patient infecté par celui-ci.

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